Volume 13, Issue 1 (March- 2024)                   Caspian J Dent Res 2024, 13(1): 11-16 | Back to browse issues page

Ethics code: IR.MUBABOL.REC.1401.172


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Zolfaghari saravi Z, Seyedmajidi M, Moudi E, Bijani F, javani A. Non-syndromic multiple odontogenic keratocysts and odontogenic cysts: Case report. Caspian J Dent Res 2024; 13 (1) :11-16
URL: http://cjdr.ir/article-1-423-en.html
, Department of Oral& Maxillofacial Pathology, Faculty of Dentistry, Babol University of Medical Science.Babol, Iran. , drzzolfaghari@gmail.com
Abstract:   (843 Views)

Odontogenic kerato Cyst (OKC) is a developmental odontogenic cyst with specific histopathologic features and clinical behavior. Several investigators suggested that OKCs should be considered benign cystic neoplasms rather than cysts. OKCs are locally aggressive benign tumors with a high recurrence rate. Usually, multiple OKCs are observed in nevoid basal cell carcinoma syndrome (NBCCS) but about 5% of OKC have multiple cysts without an accompanying syndrome.
Mutation in the human homolog of the Drosophila segment polarity gene, “patched” ((PTCH) gene) is seen. Multiple recurrent OKCs without associated systemic findings are related to the partial expression of the gene. However, few cases of non-syndromic multiple keratocystic odontogenic tumors have been reported in the literature. This case report presents a rare case of an 11-year-old boy with multiple OKCs without any syndromic association. The patient underwent surgery for multiple and recurrent cysts in the jaws over 5 years. The patient was screened for syndromic diseases and no signs or symptoms of the syndrome were found.
Keywords: Odontogenic Cysts, Gorlin Syndrome, Neoplasms.

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Type of Study: Case Report | Subject: Oral & Maxillofacial Pathology
* Corresponding Author Address: Faculty of Dentistry, Babol University of Medical Science.Babol, Iran.

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