:: Volume 11, Issue 2 (In Press ; September- 2022) ::
Caspian J Dent Res 2022, 11(2): 0-0 Back to browse issues page
Effects of full-mouth disinfection on the recurrence of helicobacter pylori infection
Arezoo Yadollahzade , Taghi Amiriani , Elham Fakhari *
,Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran. , fakhari_85@yahoo.com
Abstract:   (157 Views)
Introduction: The oral cavity has been suggested as a potential reservoir for Helicobacter pylori (H. pylori), which could be a major cause of reinfection after standard systemic therapy. The aim of this study was to evaluate the effect of full-mouth disinfection (FMD) on the recurrence of H. pylori infection.
Materials & Methods: This randomized clinical trial was conducted on 40 patients with chronic periodontitis and H. pylori infection. Of these, 20 patients received quadruple anti-H. pylori therapy only (group A) and the other 20 patients received quadruple therapy plus FMD (group B). The presence of H. pylori was detected by a 14C-urea breath test (UBT) after 1 and 6 months. Data were analyzed with SPSS 16 using the chi-square test. A value of p<0.05 was considered statistically significant.
Results: Of 40 dyspeptic patients, 15(75%) and 18(90%) of 20 in groups A and B, respectively, had a negative UBT after 4 weeks. Of the patients with successful eradication of H. pylori after 1 month, 8(53.3%) and 6(33.3%) of 15 in group A and 18 in group B, respectively had a positive UBT after 6 months. There were no statistically significant differences between the two groups in the follow-up periods (p>0.05).
Conclusion: Implementation of quadruple therapy plus FMD may reduce recurrence of the infection although further studies are recommended to confirm the results.
Keywords: Disinfection, Helicobacter Pylori, Infection Recurrence
     
Type of Study: Research Paper | Subject: Periodontics
* Corresponding Author Address: Department of Periodontics, Dental school, Golestan University of Medical Sciences, Gorgan, Iran.


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 11, Issue 2 (In Press ; September- 2022) Back to browse issues page