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:: Volume 4, Issue 2 (September- 2015) ::
Caspian J Dent Res 2015, 4(2): 8-12 Back to browse issues page
Lack of association between diabetes mellitus and oral lichen planus in Zahedan (South-East of Iran)
Tahereh Nosratzehi , Fateme Arbabi-Kalati * , Zohreh Arefpour
,Oral and Dental Disease Research Center, Department of Oral Medicine, Faculty of Dentistry, Zahedan University Of Medical Sciences, Zahdan, Iran. , farbabi@razi.tums.ac.ir
Abstract:   (5973 Views)

Introduction: Oral lichen planus (OLP) is a chronic immunological disorder with unknown etiology. Some studies have reported an association between oral lichen planus and diabetes mellitus. The aim of this study was to compare the frequency of diabetes mellitus in patients with oral lichen planus and healthy persons.

Materials & Methods: This case ‒ control study was performed on 50 patients with OLP and 50 healthy individuals. Diagnosis of OLP was confirmed by typical clinical and histopathological findings. The control group were selected randomly from healthy individuals after matching for age and sex. Blood samples were taken to achieve 5 mL for measuring fasting serum blood glucose and HbA1C. Data were analyzed using Student’s t-test.

Results: In this case ‒ control study, 50 patients with OLP (39 females, 11 males) with a mean age of 44.5±13.24 years and 50 healthy individuals (33 females, 17 males) with a mean age of 41.3±11.44 years were evaluated. The mean fasting blood glucose and HbA1C levels in patient with OLP were 95.1 ± 8.1 and 5.1±1.3 mg/dL , and 89.1±7.7 and 4.6±1.1 mg/dL in healthy individuals (P=1).

Conclusion: The frequency of diabetes mellitus was not significantly different between the case and the control groups. The results showed that diabetes mellitus does not have a direct role in the OLP etiology.

Keywords: Diabetes mellitus, Lichen planus, Oral, Etiology
Full-Text [PDF 641 kb]   (1839 Downloads)    
Type of Study: Original Article | Subject: Oral Medicine
* Corresponding Author Address: Faculty of Dentistry, Zahedan University Of Medical Sciences, Zahedan, Iran.
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Nosratzehi T, Arbabi-Kalati F, Arefpour Z. Lack of association between diabetes mellitus and oral lichen planus in Zahedan (South-East of Iran) . Caspian J Dent Res. 2015; 4 (2) :8-12
URL: http://cjdr.ir/article-1-149-en.html


Volume 4, Issue 2 (September- 2015) Back to browse issues page
مجله تحقیقات دندانپزشکی کاسپین Caspian Journal of Dental Research
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