Caspian Journal of Dental Research

Introduction: Apical seal in blood or dry root canal is a problem in endodontic treatment. Failure of apical seal causes inflammatory reaction and failure root canal treatment. Because of the sealer properties, root canal should be dry for obturation. But hydrophilic sealers can adhere to root canal walls nowadays and this problem is still controversial. This study aimed at determining the apical microleakage of AH26 and MTA Fillapex sealers in dry and bloody condition.

Methods: This experimental in vitro study was done on 48 extracted central teeth. The researchers used the Mtwo rotary files for root canal instrumentation. In this process, the teeth were divided into four groups (2 dry groups and 2 bloody groups) and two groups as positive and negative control (each group of 4 teeth). All sealers were prepared according to the factory instruction and the obturation was done with gutta-percha and sealer. After 7 days in 100% moisture condition, the teeth were placed in the ink for 3 days and then were cut across longitudinal axis and the level of microleakage was measured by stereomicroscope.Finally, the data were analyzed by SPSS software, ANOVA, Chi-Square and t-test statistical tests.

Results:The mean of MTA Fillapex and AH26 apical microleakage in blood groups were (448.61± 34.67) Mm and (429.84± 31.63) Mm respectively. The minimum microleakage belonged to AH26 sealer, but it was not significant.

Conclusion: AH26 sealer is a better barrier against microleakage in comparison with MTA Fillapx, although it is not significant. Also, the evidence suggests drying the canal leads to a better apical seal and the blood significantly increases apical microleakage. 

 Introduction: Inhibiting the pain which affects both the patients and dentists is an important factor during treating dental patients. The aim of this study was to assess the analgesic effect of two medications ibuprofen and gabapentin on the post-endodontic-therapy pain.

Methods: Forty patients who need root canal therapy with Visual Analog Scale (VAS)>40, participated in this double-blind randomized clinical trial study and randomly divided into two groups. The ibuprofen group received 800 mg ibuprofen 1 hour before the treatment and 400 mg at 6, 12 and 24 hours after the treatment procedure, and the other group received 600 mg gabapentin 1 hour before the treatment and 300 mg at 6, 12 and 24 hours after treatment. Patients recorded the intensity of pain via VAS before treatment and every hour for the first 6 h after taking the medication and then every 6 h thereafter for a total of the 48-hour period. (Two tablets of acetaminophen codeine (325mg/20mg) were given to the patients as a rescue dose.

Results: The analgesic effect of gabapentin was significantly higher than ibuprofen in 12h (p=0.035), 24h (p<0.001), and 48 h (p=0.012) after analgesic intake. It has been also shown that both medicines had analgesic effect significantly. (p<0.0001)

Conclusions: Gabapentin had greater analgesic effects on the sample group from 12 h until 48h after taking in comparison with ibuprofen so it seems that it could be an appropriate option for postoperative pain inhibition.