:: Volume 6, Issue 1 (March- 2017) ::
Caspian J Dent Res 2017, 6(1): 45-48 Back to browse issues page
Evaluation of serum Malondialdehyde level in patients with oral lichen planus
Masoumeh Mehdipour , Ali Taghavi Zenouz , Somayeh Dastanpour , Ayla Bahramian , Narges Gholizadeh, Saranaz Azari-Marhabi *
,Department of Oral Medicine, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , saranazazari@yahoo.com
Abstract:   (7151 Views)

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress in patients with oral lichen planus which is a chronic inflammatory disease with unknown etiology.

Materials & Methods: This descriptive-comparative study evaluated the oxidative stress status on twenty patients with oral lichen planus and 20 control healthy individuals based on serum level of Malondialdehyde.

Results: The mean serum Malondialdehyde levels in oral lichen planus patients and control individuals were 2.9 (±2) and 2.4 (±1.3) µg/ml, respectively, indicating no significant difference (P=0.6).

Conclusion: According to the results, role of Malondialdehyde in cellular damage and pathogenesis of oral lichen planus was not proved.

Keywords: Lichen planus, Malondialdehyde, Oxidative stress
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Type of Study: Short Communications | Subject: Oral Medicine
* Corresponding Author Address: Faculty of Dentistry, Shahid Beheshti University of Medical Sciences,Tehran, Iran.



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Volume 6, Issue 1 (March- 2017) Back to browse issues page